Atomic force microscopy captures folded ribosome bound nascent chains
Copyright policy )Atomic force microscopy captures folded ribosome bound nascent chains
Direct visualization of co-translational folding of nascent polypeptide chains is challenging. Here we present, for the first time, AFM images of large protein constructs based on the membrane binding domain of ankyrin-R, complexed with the ribosome. The characteristic "horse-shoe" shape of ankyrin-R emerging from the ribosome was captured.
- Duke University United States
Ankyrins, Models, Molecular, Protein Folding, Protein Conformation, Escherichia coli Proteins, Microscopy, Atomic Force, Protein Structure, Tertiary, Protein Biosynthesis, Escherichia coli, Peptides, Ribosomes, Protein Binding
Ankyrins, Models, Molecular, Protein Folding, Protein Conformation, Escherichia coli Proteins, Microscopy, Atomic Force, Protein Structure, Tertiary, Protein Biosynthesis, Escherichia coli, Peptides, Ribosomes, Protein Binding
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