Minute Virus of Mice Small Nonstructural Protein NS2 Interacts and Colocalizes with the Smn Protein
Copyright policy )Minute Virus of Mice Small Nonstructural Protein NS2 Interacts and Colocalizes with the Smn Protein
ABSTRACT The small nonstructural protein NS2 of the minute virus of mice (MVM) is required for efficient viral replication, although its mode of action is unclear. Here we demonstrate that NS2 and survival motor neuron protein (Smn) interact in vitro and in vivo. NS2 and Smn also colocalize in infected nuclei at late times following MVM infection.
- Arizona State University United States
- University of Missouri United States
Cell Nucleus, RNA-Binding Proteins, Nerve Tissue Proteins, SMN Complex Proteins, Viral Nonstructural Proteins, Virus Replication, Cell Line, Parvoviridae Infections, Mice, Minute Virus of Mice, Animals, Humans, Cyclic AMP Response Element-Binding Protein
Cell Nucleus, RNA-Binding Proteins, Nerve Tissue Proteins, SMN Complex Proteins, Viral Nonstructural Proteins, Virus Replication, Cell Line, Parvoviridae Infections, Mice, Minute Virus of Mice, Animals, Humans, Cyclic AMP Response Element-Binding Protein
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