Production of antibody to hepatitis A virus and hepatitis B surface antigen measured after combined hepatitis A/ hepatitis B vaccination in 242 adult volunteers
Copyright policy )Production of antibody to hepatitis A virus and hepatitis B surface antigen measured after combined hepatitis A/ hepatitis B vaccination in 242 adult volunteers
Two batches of a new hepatitis A/hepatitis B combined vaccine were tested in 242 healthy students. Three injections, given at 0, 1 and 6 months, produced seroconversion rates and hepatitis A virus (HAV) and hepatitis B surface antigen (HBsAg) antibody levels comparable to those reported after administration of separate monocomponent vaccines. The vaccine proved to be safe and well‐tolerated. Influence of host factors, such as elevated body mass index or gender, were investigated and proven to be of little influence on the immunoresponse.
- University Hospital of Lausanne Switzerland
Adult, Male, Viral Hepatitis Vaccines, Hepatitis A Vaccines, Vaccines, Synthetic, Hepatitis B Surface Antigens, Vaccination, Hepatitis A Antibodies, Humans, Female, Hepatitis B Vaccines, Hepatitis Antibodies, Vaccines, Combined, Hepatitis B Antibodies, Hepatitis A Virus, Human
Adult, Male, Viral Hepatitis Vaccines, Hepatitis A Vaccines, Vaccines, Synthetic, Hepatitis B Surface Antigens, Vaccination, Hepatitis A Antibodies, Humans, Female, Hepatitis B Vaccines, Hepatitis Antibodies, Vaccines, Combined, Hepatitis B Antibodies, Hepatitis A Virus, Human
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