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Genomics
Article . 1995 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
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Genomics
Article . 1995
Data sources: Europe PubMed Central
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Genomics
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Genetic mapping of the mouse neuromuscular mutation kyphoscoliosis

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1995 English Publisher:Elsevier BVJournal:Genomics, volume 25, pages 207-213 (issn: 0888-7543, Copyright policy )
Authors: Stephen D.M. Brown; U. Gangadharan; Roger M. Mason; M.J. Skynner; G. R. Coulton; A. Nikitopoulou; G. Blanco;

doi: 10.1016/0888-7543(95)80127-8

pmid: 7774920

Genetic mapping of the mouse neuromuscular mutation kyphoscoliosis

Abstract

The ky mouse mutant, kyphoscoliosis, exhibits a degenerative muscle disease resulting in chronic deformation of the spinal column. Using an interspecific backcross segregating the ky mutation, we have mapped the ky locus to a small region of mouse chromosome 9. ky is nonrecombinant with the microsatellites D9Mit24 and D9Mit169 and lies in a conserved linkage group that encompasses human chromosome 3. s-Laminin (LAMS) and the gene for dystrophin-associated glycoprotein 1 (DAG1), which map to human chromosome 3, are both recombinant with ky, ruling them out as candidates.

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Keywords

Genetic Markers, Membrane Glycoproteins, Base Sequence, Genetic Linkage, Molecular Sequence Data, Chromosome Mapping, Polymerase Chain Reaction, Mice, Mutant Strains, Rats, Cytoskeletal Proteins, Mice, Scoliosis, Chromosomes, Human, Pair 1, Animals, Humans, Laminin, Dystroglycans, Conserved Sequence, Crosses, Genetic, DNA Primers

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    		 11
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
11
Average
Average
Average
gold