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World Journal of Gastroenterology
Article . 2008 . Peer-reviewed
Data sources: Crossref
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World Journal of Gastroenterology
Article
License: CC BY NC
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Article . 2008
License: CC BY NC SA
Data sources: CONICET Digital
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Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy

Authors: Sookoian, Silvia Cristina; Castaño, Gustavo Osvaldo; Pirola, Carlos José;

Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy

Abstract

The pathogenesis of intrahepatic cholestasis of pregnancy (ICP), a disorder that adversely affects maternal wellbeing and fetal outcome, is unclear. However, multiple factors probably interact along with a genetic predisposition. We would like to add some comments on a paper recently published concerning the role of ABCB11 and ABCC2 polymorphisms in both ICP and contraceptive-induced cholestasis, especially in the light of our recently published findings about a positive association between ICP and ABCC2 common variants.

Country
Argentina
Keywords

Heterozygote, ABCC2, Cholestasis, Intrahepatic, Gene variants, Pregnancy, Intrahepatic cholestasis of pregnancy, https://purl.org/becyt/ford/1.6, https://purl.org/becyt/ford/3.2, Contraceptive Agents, Female, Humans, Genetic Predisposition to Disease, https://purl.org/becyt/ford/3, https://purl.org/becyt/ford/1, ATP Binding Cassette Transporter, Subfamily B, Member 11, Polymorphism, Genetic, MRP2, Genetic Variation, Membrane Transport Proteins, Multidrug Resistance-Associated Protein 2, Pregnancy Complications, ATP-Binding Cassette Transporters, Female, Multidrug Resistance-Associated Proteins

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    6
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
6
Average
Average
Average
Green
gold