One factor driving the resurgence in the popularity of macromolecular small-angle solution scattering has been the availability of new small-angle scattering instruments on third generation synchrotron sources. The high intensity, low background and the high sensitivity detectors available at these facilities has allowed the collection of better signal to noise scattering patterns, over wider ranges of scattering vector, and in less time. The result is more stringent data for modeling efforts using ever more sophisticated codes. In addition, the high fluxes and small beams delivered by these beamlines are ideal for macromolecular folding studies using stopped flow and various continuous flow micro-fluidic mixers. For folding studies, the primary advantage of SAXS over competing solution techniques, most of which are sensitive to local structural changes (such as florescence), is that it provides information on global shape changes. Here I will review a number of these applications that have been done at the BioCAT facility at the Advanced Photon Source, Argonne National Labs as well as future prospects for wider application of these techniques.