Human Nedd4L rs4149601 G Allele Generates Evolutionary New Isoform I With C2 Domain
Copyright policy )Human Nedd4L rs4149601 G Allele Generates Evolutionary New Isoform I With C2 Domain
To the Editor: We carefully read the recent article in Hypertension by Luo et al.1 They found that the human Nedd4L functional variant (rs4149601 [G/A]) shows significant functional relevance with various phenotypes of human hypertension. However, they repeatedly emphasized in the article that, “the cryptic splice variant rs4149601 (G/A) …
- Yokohama City University Japan
Polymorphism, Genetic, Endosomal Sorting Complexes Required for Transport, Nedd4 Ubiquitin Protein Ligases, Ubiquitin-Protein Ligases, Xenopus, Complement C2, Xenopus Proteins, Gene Expression Regulation, Hypertension, Animals, Humans, Protein Isoforms, Genetic Predisposition to Disease, Alleles
Polymorphism, Genetic, Endosomal Sorting Complexes Required for Transport, Nedd4 Ubiquitin Protein Ligases, Ubiquitin-Protein Ligases, Xenopus, Complement C2, Xenopus Proteins, Gene Expression Regulation, Hypertension, Animals, Humans, Protein Isoforms, Genetic Predisposition to Disease, Alleles
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