
doi: 10.1007/bf01932378
pmid: 720488
Inhibition of hepatic dimethylnitrosamine (DMN) metabolism by a variety of cyclic and acyclic nitrosamines was demonstrated. Nitrosoproline, a noncarcinogenic nitrosamine, behaved differently from the carcinogenic nitrosamines as an inhibitor for DMN-demethylase. Secondary amines corresponding to the nitrosamines inhibited DMN-demethylase in a manner similar to the nitrosamines.
Male, Nitrosamines, Liver, Proline, Animals, Oxidoreductases, N-Demethylating, Dimethylnitrosamine, Rats
Male, Nitrosamines, Liver, Proline, Animals, Oxidoreductases, N-Demethylating, Dimethylnitrosamine, Rats
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