Description of a new HLA‐DRB1 allele, DRB1*1150
Copyright policy )Description of a new HLA‐DRB1 allele, DRB1*1150
Abstract: We report the identification of a novel HLA‐DRB1*11 using sequence‐based typing. This new allele, officially named DRB1*1150, was detected while performing HLA‐DRB1 high‐resolution typing of a candidate for bone marrow transplantation. DRB1*1150 is identical to DRB1*1143 except at nucleotides 200 and 227, where a T is substituted by a C and a T by an A, respectively. These differences give rise to two amino acid substitutions at codons 38 (Val→Ala) and 47 (Phe→Tyr).
Male, Amino Acid Substitution, Base Sequence, Molecular Sequence Data, Humans, Exons, HLA-DR Antigens, Bone Marrow Transplantation, HLA-DRB1 Chains
Male, Amino Acid Substitution, Base Sequence, Molecular Sequence Data, Humans, Exons, HLA-DR Antigens, Bone Marrow Transplantation, HLA-DRB1 Chains
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