A prospective randomized study of patients between the ages of 65 and 85 with a diagnosis of degenerative arthritis was performed to evaluate the performance of the MG-II total knee arthroplasty in a cemented and a cementless application. All surgical procedures were performed by a single surgeon. The patients were randomly assigned with no consideration given to bone quality, accuracy of surgical cuts, or activity level. The cemented group of patients had an MG-II arthroplasty implanted with a cemented patellar and tibial components with a cementless femoral component. The cementless group had a totally cementless MG-II arthroplasty using a metalbacked patellar component, a cementless tibial component fixed with four screws, and a cementless femoral component. All patients were followed prospectively with clinical and radiographic data obtained at each follow-up interval. Average follow-up was 2 years. Evaluation of clinical symptoms and radiographs would indicate that cementless MG-II total knee arthroplasty is as effective as cemented hybrid MG-II total knee arthroplasty. Hybrid cemented knees recovered faster than cementless knees.