
pmid: 2676841
The chromosomal location of the murine macrophage colony-stimulating factor (Csfm) gene was determined by interspecific backcross analysis. We mapped Csfm to mouse chromosome 3, 2.5 cM distal to Ngfb and Nras and 1.3 cM proximal to Amy-2. CSFM maps to human chromosome 5q, while AMY2, NGFB, and NRAS map to human chromosome 1p. The chromosomal location of Csfm thus disrupts a previously identified conserved linkage group between mouse chromosome 3 and human chromosome 1. The location of Csfm also identifies yet another mouse chromosome that shares synteny with human chromosome 5q, a region involved in several different types of myeloid disease.
Genetic Linkage, Macrophages, Restriction Mapping, Granulocyte-Macrophage Colony-Stimulating Factor, Mice, Inbred C57BL, Blotting, Southern, Mice, Colony-Stimulating Factors, Animals, Chromosomes, Human, Pair 5, Humans, Growth Substances, Crosses, Genetic
Genetic Linkage, Macrophages, Restriction Mapping, Granulocyte-Macrophage Colony-Stimulating Factor, Mice, Inbred C57BL, Blotting, Southern, Mice, Colony-Stimulating Factors, Animals, Chromosomes, Human, Pair 5, Humans, Growth Substances, Crosses, Genetic
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 26 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
