Severe drug‐induced hypersensitivity syndrome with a shared HLA‐B allele
Copyright policy ) Gerry MacQuillan; Gerry MacQuillan; Joshua S. Davis; Damian J. Harding; David Nolan; Kavitha Subramaniam;
Severe drug‐induced hypersensitivity syndrome with a shared HLA‐B allele
We describe the first reported cases of phenytoin-related drug-induced hypersensitivity syndrome in unrelated Indigenous Australians with the same HLA-B*56:02 allele. These patients shared common clinical and pathological features, and all three were found to have the otherwise rare HLA-B allele, which might represent a novel genetic susceptibility factor for this syndrome.
- Sir Charles Gairdner Hospital Australia
- Royal Darwin Hospital Australia
- Murdoch University Australia
- Menzies School of Health Research Australia
- Royal Perth Hospital Australia
Adult, Male, Severity of Illness Index, Drug Hypersensitivity, HLA-B Antigens, Phenytoin, Humans, Anticonvulsants, Female, Alleles
Adult, Male, Severity of Illness Index, Drug Hypersensitivity, HLA-B Antigens, Phenytoin, Humans, Anticonvulsants, Female, Alleles
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).16 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 16
Average
Top 10%
Top 10%
bronze
