
doi: 10.1007/bf01311050
pmid: 2141248
Recently morbilliviruses were isolated from harbour seals (Phoca vitulina) in North West Europe (phocid distemper virus-1: PDV-1) and from Baikal seals (Phoca sibirica) in Siberia (phocid distemper virus-2: PDV-2) during outbreaks of severe disease which resembled distemper in dogs. PDV-1 and PDV-2 were passaged in SPF dogs, in which they caused distemper-like disease symptoms, and were subsequently passaged in Vero cells in which they caused cytopathic changes. PDV-1, PDV-2, and canine distemper virus (CDV) were compared with respect to their biological, morphological, physical, protein chemical, and antigenic properties. It was concluded that PDV-1 should be considered a newly recognized member of the genus Morbillivirus, whereas PDV-2 proved to be quite similar if not identical to CDV.
Seals, Earless, Antibodies, Viral, Respirovirus Infections, Caniformia, Disease Outbreaks, Specific Pathogen-Free Organisms, Viral Proteins, Dogs, Paramyxoviridae, Immunologic Techniques, Animals, Serial Passage, Antigens, Viral
Seals, Earless, Antibodies, Viral, Respirovirus Infections, Caniformia, Disease Outbreaks, Specific Pathogen-Free Organisms, Viral Proteins, Dogs, Paramyxoviridae, Immunologic Techniques, Animals, Serial Passage, Antigens, Viral
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