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Mechanisms of Development
Article
License: Elsevier Non-Commercial
Data sources: UnpayWall
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Mechanisms of Development
Article . 2000
License: Elsevier Non-Commercial
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Mechanisms of Development
Article . 2000 . Peer-reviewed
License: Elsevier Non-Commercial
Data sources: Crossref
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Expression of Chx10 and Chx10-1 in the developing chicken retina

Authors: Amy Chen, C.-M; Cepko, Constance L;

Expression of Chx10 and Chx10-1 in the developing chicken retina

Abstract

We have isolated full-length cDNAs of chick Chx10 and Chx10-1, two members of the paired type homeobox/CVC gene family. A comparison of sequences suggests that Chx10 is closely related to Alx/Vsx-2 and Vsx-2 of zebrafish and goldfish, respectively; while Chx10-1 is closely related to Vsx-1 of zebrafish and goldfish. Chx10 and Chx10-1 are expressed in the early retinal neuroepithelium, but not in the pigment epithelium and lens. The expression of Chx10 is present in most retinal neuroblasts, while Chx10-1 exhibits a novel pattern along the nasotemporal border. In the differentiating retina, both Chx10 and Chx10-1 are restricted to bipolar cells and are maintained at a low level in bipolar cells of the mature retina.

Related Organizations
Keywords

Homeodomain Proteins, Embryology, Sequence Homology, Amino Acid, Molecular Sequence Data, Gene Expression, Chick Embryo, Retina, Avian Proteins, Animals, Tissue Distribution, Amino Acid Sequence, Eye Proteins, Developmental Biology, Transcription Factors

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    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
95
Top 10%
Top 10%
Top 10%
hybrid