Mechanisms of Mammalian Selenocysteyl-tRNA Synthesis

Takaharu Mizutani; Hiroshi Kurata; Kenichiro Yamada

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Phosphorus Sulfur and Silicon and the Related Elements

Article . 1992 . Peer-reviewed

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https://dx.doi.org/10.1080/104...

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Mechanisms of Mammalian Selenocysteyl-tRNA Synthesis

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1992 English Publisher:Informa UK LimitedJournal:Phosphorus, Sulfur, and Silicon and the Related Elements, volume 67, pages 425-428 (issn: 1042-6507, eissn: 1563-5325,

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Authors: Takaharu Mizutani; Hiroshi Kurata; Kenichiro Yamada;

doi: 10.1080/10426509208045865

Mechanisms of Mammalian Selenocysteyl-tRNA Synthesis

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Abstract

Abstract The mechnisms of synthesis of mammalian selenocysteyl-tRNA were studied with murine active enzyme fractions. (75Se)Selenocysteyl-tRNA was synthesized in vitro by 500kDa protein from seryl-tRNA and (75Se)HSe-, which should be activated with ATP by 20kDa protein. This and other factors in mamalian systems are compared with those in Escherichia coli.

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Nagoya City University
Japan

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ChemInform Abstract: Mechanisms of Mammalian Selenocysteyl‐tRNA Synthesis
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