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Innovative Drug Delivery Systems in Cardiovascular Medicine

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1987Publisher:Elsevier BVJournal:Cardiology Clinics, volume 5, pages 703-716 (issn: 0733-8651,

Authors: David Sherman; William H. Frishman; Donald A. Feinfeld;

doi: 10.1016/s0733-8651(18)30522-8

pmid: 3331321

Innovative Drug Delivery Systems in Cardiovascular Medicine

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Abstract

Innovative drug delivery systems have been developed for nifedipine and clonidine that prolong the pharmacologic activity of the medications, allowing once daily dosing. The nifedipine-GITS (gastrointestinal therapeutic system) tablet formulation and the clonidine-TTS (transcutaneous delivery system) patch may also reduce side effects in patients while preserving the therapeutic efficacy of the origin drug formulations (nifedipie capsule, clonidine tablet).

Related Organizations

Yeshiva University
United States
Albert Einstein College of Medicine
United States
Jacobi Medical Center
United States

Keywords

Clinical Trials as Topic, Nifedipine, Delayed-Action Preparations, Hypertension, Humans, Administration, Cutaneous, Clonidine, Angina Pectoris

6 Research products, page 1 of 1

A randomized controlled trial on the blood pressure–lowering effect of amlodipine and nifedipine‐GITS in sustained hypertension
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Transdermal clonidine application: Long-term results in essential hypertension
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Comparative efficacy of two long-acting formulations of nifedipine in the treatment of hypertension. The Switch Study Investigators.
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Effects of Nifedipine-GITS on Left Ventricular Mass and Left Ventricular Filling
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Early Experience with Dobutamine Stress Testing and Cardiac Cine‐tomographic Imaging in the Elderly: Antianginal Effects of Nifedipine‐GITS
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PEN1: QUALITY-OF-LIFE-EVALUATION OF THE GERMAN S.A.T.-TRIAL - COMPARISON OF SF-36, EUROQOL, TIME-TRADE-OFF METHOD AND WILLINGNESS-TO-PAY
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