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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Zentralblatt für Vet...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Zentralblatt für Veterinärmedizin Reihe B
Article . 2010 . Peer-reviewed
License: Wiley TDM
Data sources: Crossref
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Dynamics of Nucleic Acids and Total Proteins in the Thymus and the Bursa of Fabricius of Chickens with Rous Sarcoma

Authors: V, Toma; R, Giurgea; M, Borşa; S, Ilyes;

Dynamics of Nucleic Acids and Total Proteins in the Thymus and the Bursa of Fabricius of Chickens with Rous Sarcoma

Abstract

Summary In Rous sarcoma-transplanted young Studler chickens, the reactions of thymus and bursa reflect the development of the tumour. A hyperplasia of both glands is observed during the first three days: the weight of the glands, and their contents of nucleic acids and proteins increase. Thereafter, a progressive, constant and irreversible involution of the glands occurs, though no tumour is detectable. This involution is maximally enhanced in the final phase of cancer development. The observations are discussed from the point of view of the correlation of antitumoral defence reactions with stress phenomena. Zusammenfassung Die Dynamik der Nukleinsauren und Gesamtproteine in Thymus und Bursa Fabricii von Huhnern mit Rous-Sarkom Bei jungen Studler Huhnern mit transplantierten Rous-Sarkomen reflektieren die Reaktionen von Thymus und Bursa die Entwicklung des Tumors. Wahrend der ersten 3 Tage kommt es zu einer Hyperplasie beider Organe; das Gewicht der Organe und ihr Gehalt an Nukleinsauren und Proteinen nimmt zu. Danach kommt es zu einer fortschreitenden, konstanten und irreversiblen Involution der Organe, obwohl kein Tumor nachweisbar ist. In der Schlusphase der Tumorentwicklung wird diese Involution stark beschleunigt. Die Beobachtungen werden diskutiert im Hinblick auf die Korrelation von Stress-Phanomenen und Tumorabwehr. Resume La dynamique des acides nucleiques et les proteines totales dans le thymus et la bourse de Fabricius chez des poules atteintes de sarcome de Rous Lors de transplantation de sarcomes de Rous chez de jeunes poules Studler, les reactions du thymus et de la bourse de Fabricius refleterent le developpement de la tumeur. Il y eut une hyperplasie des deux organes lors des 3 premiers jours; le poids des organes et leur contenu en acides nucleiques et en proteines augmenterent. Il s'en suivit une involution progressive, constante et irreversible des organes bien qu'aucune turneur ne fut decelable. Cette involution fut forternent acceleree dans la phase finale du developpement de la tumeur. Les resultats sont discutes du point de vue de la correlation des phenomenes de stress et de la defense de la tumeur. Resumen La dinamica de los acidos nucleicos y proteinas totales en el timo y bolsa de Fabricio de gallinas con sarcoma de Rous En gallinas jovenes de la raza Studler con sarcomas de Rous transplantados reflejan las reacciones de timo y bolsa de Fabricio el desarrollo tumoral. Durante los 3 dias primeros se produce una hiperplasia en ambos organos; aumentan el peso de los organos y su tasa en acidos nucleicos y proteinas. Despues se registra una involucion constante, progresiva e irreversible de los organos, aunque no se pueda identificar ningun tumor. En la fase final del desarrollo tumoral se halla muy acelerada esta involucion. Se discuten las observaciones hechas con respecto a la correlacion de fenomenos de stress y la defensa antitumoral.

Keywords

Sarcoma, Avian, Bursa of Fabricius, Nucleic Acids, Animals, Proteins, Organ Size, Thymus Gland, Chickens

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
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