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BiG-MAP: an Automated Pipeline To Profile Metabolic Gene Cluster Abundance and Expression in Microbiomes

Authors: Victória Pascal Andreu; Hannah E. Augustijn; Koen van den Berg; Justin J. J. van der Hooft; Michael A. Fischbach; Marnix H. Medema;

BiG-MAP: an Automated Pipeline To Profile Metabolic Gene Cluster Abundance and Expression in Microbiomes

Abstract

Microbes play an increasingly recognized role in determining host-associated phenotypes by producing small molecules that interact with other microorganisms or host cells. The production of these molecules is often encoded in syntenic genomic regions, also known as gene clusters.

Keywords

metagenomics, metatranscriptomics, microbiome-associated phenotype, Methods and Protocols, Biosynthesis, metabolomics, Microbiology, Specialized metabolism, QR1-502, metabolic gene cluster, Metabolic gene cluster, Metabolomics, Microbiomeassociated phenotype, Metagenomics, Microbiome, biosynthesis, Metatranscriptomics

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
downloads
OpenAIRE UsageCountsDownloads provided by UsageCounts
27
Top 10%
Average
Top 10%
10
7
Green
gold