
pmid: 21459456
The authors studied the prevalence of the human leukocyte antigen (HLA) Class I gene in 136 (85 male, 51 female) India-born schizophrenia patients residing in and around the Siliguri subdivision of West Bengal by the PCR-SSP method. The control group consisted of 150 age- and sex-matched healthy individuals from the same ethnic group as the patients. Increased frequency of HLA A*03 as well as decreased frequencies of HLA A*31 and HLA B*51, was noted. The study suggests the possible existence of a susceptibility locus for schizophrenia within the HLA region.
Adult, Male, Genotype, Histocompatibility Antigens Class I, Genes, MHC Class I, India, Middle Aged, Young Adult, Gene Frequency, HLA Antigens, Case-Control Studies, Humans, Female, Genetic Predisposition to Disease, Genetic Testing
Adult, Male, Genotype, Histocompatibility Antigens Class I, Genes, MHC Class I, India, Middle Aged, Young Adult, Gene Frequency, HLA Antigens, Case-Control Studies, Humans, Female, Genetic Predisposition to Disease, Genetic Testing
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