The aim is to study the main TORCH infections during pregnancy in women with a history of endocrine and inflammatory infertility.Materials and research methods. We studied the spectrum of TORCH infections during pregnancy in 420 women. The division of pregnant women into groups is based on the factor of infertility: Group I - 100 pregnant women with a history of endocrine infertility, Group II - 200 pregnant women with a history of infertility of inflammatory origin, Group III - 60 pregnant women with a history of combined infertility: inflammatory genesis with endocrine, group IV (control) - 60 healthy pregnant women who had no history of infertility. Enzyme-linked immunosorbent assay (ELISA) for the specificity of IgM antibodies, IgG to Toxoplasma gondii, CMV, Rubella, HSV 2, Chlamydia trachomatis. These studies were performed by solid-phase enzyme-linked immunosorbent sandwich analysis using standard sets of monoclonal antibodies from Abbott (USA) on a WALA C 1420 immunoassay apparatus (Perkin Elmer).Research results. Out of 420 pregnant women examined for the presence of IgG to Toxoplasma, 204 (48.6%) were seropositive: Group I - 39 (39%), Group II - 120 (60%), Group III - 30 (50%), control (IV) - 15 (25%). Serological marker - Ig G to herpes simplex virus type 2 is set: I - 10 (10%), II - 30 (15%), III - 10 (16.7%), control - 2 (3.3%). The presence of antiherpetic Ig M is single. Specific Ig G antibodies to cytomegalovirus in most subjects were found: I - 85 (85%), II - 180 (90%), III - 55 (91.7%), IV - 52 (86.6%); in all these subjects the level of Ig M was negative. When examining pregnant women of all groups for rubella, there was one pregnant woman in each group who was not immune to it. Therefore, these pregnant women were at risk. The level of chlamydial infection was in pregnant women of groups II and III. Of the 420 pregnant women examined for the presence of IgG to chlamydia, 111 (26.4%) were seropositive: Group I - 7 (7%), Group II - 75 (37.5%), Group III -25 (41, 7%), control (IV) - 4 (6.7%).Conclusions. Studying the spectrum of infections of the TORCH-complex in women with a history of various types of infertility, we see a greater prevalence in pregnant women from groups III and II. Moreover, the identified pathogens were mainly in associations.