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pmid: 11893486
Covalent modifications of the amino termini of the core histones in nucleosomes have important roles in gene regulation. Research in the past two years reveals these modifications to consist of phosphorylation, methylation and ubiquitination, in addition to the better-characterized acetylation. This multiplicity of modifications, and their occurrence in patterns and dependent sequences, argues persuasively for the existence of a histone code.
Saccharomyces cerevisiae Proteins, Acetylation, Histone-Lysine N-Methyltransferase, Methyltransferases, Methylation, Chromatin, Histones, Gene Expression Regulation, Acetyltransferases, Histone Methyltransferases, Animals, Humans, Protein Methyltransferases, Phosphorylation, Protein Processing, Post-Translational, Histone Acetyltransferases
Saccharomyces cerevisiae Proteins, Acetylation, Histone-Lysine N-Methyltransferase, Methyltransferases, Methylation, Chromatin, Histones, Gene Expression Regulation, Acetyltransferases, Histone Methyltransferases, Animals, Humans, Protein Methyltransferases, Phosphorylation, Protein Processing, Post-Translational, Histone Acetyltransferases
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 1K | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 1% | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 0.1% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 0.1% |