A gene-driven approach to the identification of ENU mutants in the mouse
Copyright policy ) Emma L, Coghill; Alison, Hugill; Nick, Parkinson; Claire, Davison; Peter, Glenister; Sian, Clements; Jackie, Hunter; +2 Authors
Emma L, Coghill; Alison, Hugill; Nick, Parkinson; Claire, Davison; Peter, Glenister; Sian, Clements; Jackie, Hunter; Roger D, Cox; Steve D M, Brown;
A gene-driven approach to the identification of ENU mutants in the mouse
The construction of parallel archives of DNA and sperm from mice mutagenized with ethylnitrosurea (ENU) represents a potentially powerful and rapid approach for identifying point mutations in any gene in the mouse genome. We provide support for this approach and report the identification of mutations in the gene (Gjb2) encoding connexin 26, using archives established from the UK ENU mutagenesis program.
- GlaxoSmithKline (United Kingdom) United Kingdom
- Cellzome, GSK, Middlesex, UK.
Male, Heterozygote, Mice, Inbred BALB C, Mice, Inbred C3H, Mice, Mutant Strains, Mice, Ethylnitrosourea, Mutation, Animals, Female, Alleles, Mutagens
Male, Heterozygote, Mice, Inbred BALB C, Mice, Inbred C3H, Mice, Mutant Strains, Mice, Ethylnitrosourea, Mutation, Animals, Female, Alleles, Mutagens
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These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 159
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