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Functional Changes Of Fetal Muscle Acetylcholine Receptor During Mouse Development

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1998 Italy English Publisher:American Physiological SocietyJournal:Physiology, volume 13, pages 247-251 (issn: 1548-9213, eissn: 1548-9221,

Authors: GRASSI, Francesca; EUSEBI, Fabrizio;

doi: 10.1152/physiologyonline.1998.13.5.247

pmid: 11390797

handle: 11573/246379

Functional Changes Of Fetal Muscle Acetylcholine Receptor During Mouse Development

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Abstract

In developing muscles in vivo and in vitro, the acetylcholine receptor γ-subunit exists in two splice variants, conferring different single-channel open durations (τop) to reconstituted receptors. In mouse muscles, τop changes around birth, possibly as receptors incorporate either variant of γ-subunit. This might be relevant to the concomitant maturation of muscle innervation.

Country

Italy

Related Organizations

Keywords

acetylcholine receptor; alternative splicing; kinetic properties; muscle development

6 Research products, page 1 of 1

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