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Microbiome and Antimicrobial Resistance Gene Dynamics in International Travelers

Authors: Langelier, Charles; Graves, Michael; Kalantar, Katrina; Caldera, Saharai; Durrant, Robert; Fisher, Mark; Backman, Richard; +3 Authors

Microbiome and Antimicrobial Resistance Gene Dynamics in International Travelers

Abstract

AbstractWe engaged metagenomic next generation sequencing to longitudinally assess the gut microbiota and antimicrobial resistomes of international travelers to understand global exchange of resistant organisms. Travel resulted in an increase in antimicrobial resistance genes and a greater proportion ofEscherichiaspecies within gut microbial communities without impacting diversity.

Keywords

Gene Transfer, Horizontal, microbiome, Infectious and parasitic diseases, RC109-216, Communicable Diseases, Databases, Genetic, Humans, antimicrobial resistance, resistome, Travel, Microbiota, R, Dispatch, Computational Biology, High-Throughput Nucleotide Sequencing, Drug Resistance, Microbial, Biodiversity, travel medicine, extended-spectrum β-lactamase, ESBL, Medicine, Metagenome, Metagenomics, Travel-Related Illness

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    36
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
36
Top 10%
Top 10%
Top 10%
Green
gold