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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Medical Physicsarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Medical Physics
Article . 1986 . Peer-reviewed
License: Wiley Online Library User Agreement
Data sources: Crossref
Medical Physics
Article . 1987
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Monte Carlo dosimetry for 125I and 60Co in eye plaque therapy

Authors: Hung-Sheng Tsao; Marvin Rotman; Charles Vialotti; Sou-Tung Chiu-Tsao; Keran O'Brien; R. Sanna; Samuel Packer; +1 Authors

Monte Carlo dosimetry for 125I and 60Co in eye plaque therapy

Abstract

Monte Carlo calculations of radiation dosimetry using morse code are performed for 125I and 60Co point sources in a cylindrical head phantom that simulates the geometry of eye plaque therapy for choroidal melanoma. We obtain the dose variation in the eye at submillimeter intervals over distances as close as 1 mm and up to 2.5 cm from the source. The calculations for 125I are performed for the phantom media of water, protein, and a homogenized protein–water mixture simulating the composition of the eye. Relative dose functions for 125I for these phantom media are fitted to second‐degree polynomials. Agreement is found with published results. The relative dose function for 60Co at eye position in the water head phantom is fitted to a third‐degree polynomial and compared with that for 60Co at the center of a large water sphere. A boundary effect due to the head phantom–air interface on the dose distribution for 60Co is demonstrated. The dose falloff with distance is faster for the eye geometry compared with the bulk geometry. We also show that the relative dose distributions within the tumor are comparable for 125I and 60Co by comparing their relative dose functions. This result is consistent with the success of clinical trials of large melanoma treatments with 125I plaques.

Keywords

Iodine Radioisotopes, Models, Anatomic, Choroid Neoplasms, Biophysics, Humans, Radiotherapy Dosage, Cobalt Radioisotopes, Melanoma, Monte Carlo Method, Biophysical Phenomena

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    citations
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    37
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
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    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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Found an issue? Give us feedback
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
37
Top 10%
Top 1%
Average
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