The hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin
Copyright policy )NIH| Spectrum Stanford Center for clinical and Translational Research and Education ,
NIH| Molecular characterization of cardiomyopathy mutations in human cardiac myosin ,
NIH| Myosin Movement in Vitro - Molecular Characterization ,
NIH| Expanding the utility of transcriptional bacterial computing
Saswata S. Sarkar; Darshan V. Trivedi; Makenna M. Morck; Arjun S. Adhikari; Shaik N. Pasha; Kathleen M. Ruppel; James A. Spudich;
The hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin
Hypertrophic cardiomyopathy–causing mutations disrupt a key regulatory off state of myosin in thick filaments.
Models, Molecular, Binding Sites, Protein Conformation, Cardiomyopathy, Hypertrophic, Myosins, Myocardial Contraction, Actins, Ventricular Myosins, Structure-Activity Relationship, Amino Acid Substitution, Mutation, Humans, Genetic Predisposition to Disease, Research Articles, Alleles, Protein Binding
Models, Molecular, Binding Sites, Protein Conformation, Cardiomyopathy, Hypertrophic, Myosins, Myocardial Contraction, Actins, Ventricular Myosins, Structure-Activity Relationship, Amino Acid Substitution, Mutation, Humans, Genetic Predisposition to Disease, Research Articles, Alleles, Protein Binding
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).79 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 1% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 1%
selected citations
Citations provided by BIP!
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 79
Top 1%
Top 10%
Top 1%
Green
gold
