Role of NF-κB-Dependent Signaling in the Growth Capacity of Mesenchymal Progenitor Cells Under the Influence of Basic Fibroblast Growth Factor
Copyright policy ) G N, Zyuz'kov; M G, Danilets; A A, Ligacheva; V V, Zhdanov; E V, Udut; L A, Miroshnichenko; A V, Chaikovskii; +6 Authors
G N, Zyuz'kov; M G, Danilets; A A, Ligacheva; V V, Zhdanov; E V, Udut; L A, Miroshnichenko; A V, Chaikovskii; E V, Simanina; E S Trofi, Mova; M Yu, Minakova; E A, Losev; V V, Udut; A M, Dygai;
Role of NF-κB-Dependent Signaling in the Growth Capacity of Mesenchymal Progenitor Cells Under the Influence of Basic Fibroblast Growth Factor
We studied the in vitro role of NF-κB-dependent signaling in the growth capacity of mesenchymal progenitor cells upon stimulation by basic fibroblast growth factor. Proliferative activity of progenitor cells was suppressed by specifi c inhibitors of this transcription factor (NF-κB), oridonin and aurothiomalate. These inhibitors had no effect on differentiation of fibroblast CFU.
Mice, Inbred CBA, NF-kappa B, Animals, Fibroblast Growth Factor 2, Mesenchymal Stem Cells, Cell Cycle Checkpoints, Second Messenger Systems, Cells, Cultured, Cell Proliferation
Mice, Inbred CBA, NF-kappa B, Animals, Fibroblast Growth Factor 2, Mesenchymal Stem Cells, Cell Cycle Checkpoints, Second Messenger Systems, Cells, Cultured, Cell Proliferation
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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