Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia
Copyright policy )NIH| Integrated Variation Detection Annotation and Analysis ,
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Siwei Zhang; Siwei Zhang; Tade Souaiaia; Tade Souaiaia; Hanwen Zhang; Jubao Duan; Jubao Duan; +12 Authors
Siwei Zhang; Siwei Zhang; Tade Souaiaia; Tade Souaiaia; Hanwen Zhang; Jubao Duan; Jubao Duan; Marc P. Forrest; Chris Armoskus; Chris Armoskus; Oleg V. Evgrafov; Oleg V. Evgrafov; James A. Knowles; James A. Knowles; Abolfazl Doostparast Torshizi; Abolfazl Doostparast Torshizi; Kai Wang; Kai Wang; Kai Wang;
Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia
TCF4 acts as a master regulator affecting expression of other genes, which may contribute to the development of schizophrenia.
United States
- Northwestern University United States
- University of Pennsylvania United States
- King’s University United States
- University of California System United States
- Columbia University United States
Adult, Male, Neurons, 570, Induced Pluripotent Stem Cells, Neuroepithelial Cells, 610, Prefrontal Cortex, Transcription Factor 4, Neural Stem Cells, Olfactory Mucosa, Case-Control Studies, Schizophrenia, Humans, Gene Regulatory Networks, Genetic Predisposition to Disease, Research Articles, Cells, Cultured
Adult, Male, Neurons, 570, Induced Pluripotent Stem Cells, Neuroepithelial Cells, 610, Prefrontal Cortex, Transcription Factor 4, Neural Stem Cells, Olfactory Mucosa, Case-Control Studies, Schizophrenia, Humans, Gene Regulatory Networks, Genetic Predisposition to Disease, Research Articles, Cells, Cultured
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 63
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