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Insulin-like growth factor II receptor as a multifunctional binding protein

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1987Publisher:Springer Science and Business Media LLCJournal:Nature, volume 329, pages 301-307 (issn: 0028-0836, eissn: 1476-4687,

Authors: Richard A. Roth; William J. Rutter; Jeffrey C. Edman; David O. Morgan; David O. Morgan; Michele C. Smith; Victor A. Fried; +1 Authors

doi: 10.1038/329301a0

pmid: 2957598

Insulin-like growth factor II receptor as a multifunctional binding protein

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  (6)
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Abstract

The primary structure of human insulin-like growth factor II receptor, predicted from the complementary DNA sequence, reveals a transmembrane receptor molecule with a large extracellular domain made up of fifteen repeat sequences and a small region homologous to the collagen-binding domain of fibronectin. The structural and biochemical features of the IGF-II receptor appear identical to those of the cation-independent mannose-6-phosphate receptor.

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Stanford University
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Keywords

Base Sequence, DNA, Recombinant, Membrane Proteins, Receptors, Somatomedin, DNA, Receptor, IGF Type 2, Receptor, Insulin, Rats, Xenopus laevis, Sequence Homology, Nucleic Acid, Oocytes, Animals, Humans, Amino Acid Sequence, Carrier Proteins, Repetitive Sequences, Nucleic Acid

6 Research products, page 1 of 1

Insulin-like growth factor type 2 receptor
2017IsRelatedTo
Homo sapiens (human) hypothetical protein
2018IsRelatedTo
Cation-independent mannose-6-phosphate receptor
2017IsRelatedTo
Homo sapiens (human) partial insulin-like growth factor type II receptor
2018IsRelatedTo
Homo sapiens IGF2R gene (subclone pEX1-P)
2018IsRelatedTo
Human mRNA for insuline-like growth factor II receptor
2018IsRelatedTo

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	940
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 0.1%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 0.1%