The CAIS Mobility Safety Protocol (CMSP v1.0) defines the world’s first consciousness-based safety and risk-reduction framework for autonomous, connected, and semi-autonomous mobility systems. This document applies the Consciousness–Aptamer Interface Standard (CAIS v1.0) to safety-critical mobility operations, including:• collision-risk reduction• driver/passenger attentional stability• cognitive-state monitoring• physiological-coherence mapping• multi-vehicle cascade-failure prevention• fleet-level risk-model harmonization CMSP v1.0 provides:(1) a standardized cognitive-physiological measurement pipeline,(2) an ISO/NIST-compatible technical specification,(3) a legally binding prior-art declaration, and(4) a safety-operating framework for AV/ADAS engineering teams. This record is an official supplement to the CAIS global standard suite authored by Dr. Jinho Lee, including:• CAIS v1.0 — Consciousness–Aptamer Interface Standard• CFE⁺ Framework — unified VCE/CRI/CFI consciousness metrics• COS v1.0 — Consciousness Operating System Summary• UCOS v1.0 — Consciousness OS Master Summary• CCR v1.0 — Consciousness Civilization Roadmap• GCMI v1.0 — Global Consciousness Measurement Initiative All materials are released for scientific replication, mobility-safety engineering, AI safety integration, and civilization-scale prior-art record.