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Biological and Pharmaceutical Bulletin
Article . 1998 . Peer-reviewed
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Biological and Pharmaceutical Bulletin
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Biological and Pharmaceutical Bulletin
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Studies on Inhibitory Activities of Fukiic Acid Esters on Germination, .ALPHA.-Amylase and Carboxypeptidase A.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1998 English Publisher:Pharmaceutical Society of JapanJournal:Biological and Pharmaceutical Bulletin, volume 21, pages 997-999 (issn: 0918-6158, eissn: 1347-5215, Copyright policy )
Authors: Hiroshi Tsujibo; Akiko Kusano; Atsushi Numata; Makio Shibano; Genjiro Kusano; Yukiko Okamoto; Yoshihiko Inamori; +1 Authors

doi: 10.1248/bpb.21.997

pmid: 9781856

Studies on Inhibitory Activities of Fukiic Acid Esters on Germination, .ALPHA.-Amylase and Carboxypeptidase A.

Abstract

Fukinolic acid (1) and cimicifugic acid A (2), caffeic acid analogs, as well as rosmarinic acid (3) and caffeic acid (4) showed inhibition on seed germination and seedling growth. The potency of 1 and 2 was comparable with that of 3. Compounds 1 and 2 also showed strong inhibitory activities as well as 3 and 4 on alpha-amylase. The activity of 1 was higher than that of acarbose used as a positive control, and its 50% inhibitory concentration (IC50) was 2.41 x 10(-5) M. Compounds 1 and 2 also showed inhibitory activities strong as 3 and stronger than 4 on carboxypeptidase A. The activities of 1 and 2 were higher than that of 1, 10-phenanthroline used as a positive control.

Related Organizations
Keywords

Plants, Medicinal, Carboxypeptidases A, Phenylpropionates, Plant Extracts, Esters, Germination, Succinates, Carboxypeptidases, Caffeic Acids, Seeds, Enzyme Inhibitors, alpha-Amylases, Phenylacetates

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 21
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    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
21
Average
Top 10%
Top 10%
gold
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