Mouse Thioredoxin Gene Maps on Chromosome 4, whereas Its Pseudogene Maps on Chromosome 1
Copyright policy )Mouse Thioredoxin Gene Maps on Chromosome 4, whereas Its Pseudogene Maps on Chromosome 1
Thioredoxins are involved in various biochemical systems and mediate both redox and nonredox functions. In mammalian cells, thioredoxin functions as an endogenous glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF) that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn maps to Chr 4, whereas Txn-ps1 maps to the proximal region of Chr 1.
- Duke University United States
- Kyoto University Japan
- Duke University Hospital United States
- Merck & Co. United States
- Duke University Health System United States
Mice, Inbred C3H, Chromosome Mapping, Muridae, Meiosis, Mice, Thioredoxins, Genes, Species Specificity, Animals, Humans, Crosses, Genetic, Pseudogenes
Mice, Inbred C3H, Chromosome Mapping, Muridae, Meiosis, Mice, Thioredoxins, Genes, Species Specificity, Animals, Humans, Crosses, Genetic, Pseudogenes
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