Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity
Copyright policy )Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity
AAVs are widely studied therapeutic gene delivery vectors. However, preexisting antibodies and their detrimental effect on therapeutic efficacy are a primary challenge encountered during clinical trials.
- Florida Southern College United States
- Florida State University
- University of California Los Angeles
- Université du Québec Canada
- University of California, Los Angeles United States
Models, Molecular, 570, receptor, Genetic Vectors, 610, adeno-associated virus, CHO Cells, Cross Reactions, Adeno-Associated Virus, Parvovirus, Sialic Acid, Epitopes, Capsid, Cricetulus, antibody, Cricetinae, capsid, Animals, Humans, Antibody, Cryo-EM, parvovirus, Cryoelectron Microscopy, AAV, Gene Therapy, Dependovirus, gene therapy, N-Acetylneuraminic Acid, sialic acid, Human Sera, cryo-EM, Capsid Proteins, Receptor, human sera
Models, Molecular, 570, receptor, Genetic Vectors, 610, adeno-associated virus, CHO Cells, Cross Reactions, Adeno-Associated Virus, Parvovirus, Sialic Acid, Epitopes, Capsid, Cricetulus, antibody, Cricetinae, capsid, Animals, Humans, Antibody, Cryo-EM, parvovirus, Cryoelectron Microscopy, AAV, Gene Therapy, Dependovirus, gene therapy, N-Acetylneuraminic Acid, sialic acid, Human Sera, cryo-EM, Capsid Proteins, Receptor, human sera
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