<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Polar expeditions — provisioning the centrosome for mitosis

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2003 English Publisher:Springer Science and Business Media LLCJournal:Nature Cell Biology, volume 5, pages 505-511 (issn: 1465-7392, eissn: 1476-4679,

Authors: Sarah P. Blagden; David M. Glover;

doi: 10.1038/ncb0603-505

pmid: 12776127

Polar expeditions — provisioning the centrosome for mitosis

- Summary
- Subjects
- Related research
  (43)
- Metrics

Abstract

It is now clear that both centrioles and their surrounding pericentriolar material (PCM) are capable of self-assembly. Whereas centrioles are normally duplicated during G1-S phase, PCM components may be loaded onto centrosomes in both a microtubule-dependent and -independent manner at all stages of the cell cycle. Centrosomes enlarge dramatically after mitotic entry, when both Aurora A and Polo-like kinases cooperate to recruit additional gamma-tubulin ring complexes and microtubule-associated proteins to assist spindle formation.

Related Organizations

University of Cambridge
United Kingdom

Keywords

Centrosome, Dyneins, Mitosis, Protein Serine-Threonine Kinases, Microtubules, Models, Biological, Aurora Kinases, Tubulin, Animals, Drosophila Proteins, Humans, Microtubule-Associated Proteins, Centrioles

43 Research products, page 1 of 5

Gamma-tubulin complex component
2017IsRelatedTo
Centrosomin, isoform N
2017IsRelatedTo
Transforming acidic coiled-coil protein, isoform C
2017IsRelatedTo
Centrosomin, isoform D
2017IsRelatedTo
Transforming acidic coiled-coil protein, isoform K
2017IsRelatedTo
Transforming acidic coiled-coil protein, isoform D
2017IsRelatedTo
Aurora
2017IsRelatedTo
Gamma-tubulin complex component 3
2018IsRelatedTo
Centrosomin, isoform I
2017IsRelatedTo
Protein mini spindles
2017IsRelatedTo

chevron_left
1
2
3
4
5
chevron_right

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	115
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%