Deliverable 2.1, part of BY-COVID WP2, will develop the infrastructure required to facilitate access to a broad portfolio of data sources relevant to COVID-19 in preparation for future outbreak responses. Importantly, WP2 will collate, connect, and harmonise data sources within domains and disciplines in preparation for deeper cross-domain harmonisation efforts in WP3 and in connection with pathogen genome data (WP1). WP2 will further collate data governance models, metadata descriptions and access mechanisms ensuring full alignment with WP3 on the acquisition, curation and use of metadata from data sources. Interaction with WP4 will enable the development of tools for processing and harmonising metadata across data sources within the same domain. It also explores the initial infrastructure set-up activities undertaken to provide the capability for the rapid onboarding of resources in the future.