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Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE-5

Name: Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE-5
Keywords: 3. Good health

appsOther research productkeyboard_double_arrow_right Image 01 Jan 2011Publisher:figshare

Authors: Prato, Mauro; Gallo, Valentina; Giribaldi, Giuliana; Arese, Paolo;

doi: 10.6084/m9.figshare.88572 , 10.6084/m9.figshare.88572.v1

Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE-5

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Abstract

). After 3 h phagocytosis and a further incubation during 48 h, IL1-beta levels were measured by ELISA in cell supernatants. Data are given as ng IL-1beta/ml supernatant (mean values ± SD of six independent experiments). Data were analysed for significance by Student's t-test. Significance of differences (column numbers): trophozoite-fed(3)/HZ-fed(5) vs unfed-(1)/nonparasitized RBC-fed(2) monocytes, p < 0.05; latex-fed(4) vs unfed-(1)/nonparasitized RBC-fed(2) monocytes, n.s.; trophozoite-fed(3) vs HZ-fed(5) monocytes, n.s.Copyright information:Taken from "Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE"http://www.malariajournal.com/content/7/1/157Malaria Journal 2008;7():157-157.Published online 18 Aug 2008PMCID:PMC2529304.

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