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Genomics
Article . 1988 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
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Genomics
Article . 1988
Data sources: Europe PubMed Central
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Genomics
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Establishment of a molecular genetic map of distal mouse chromosome 1: Further definition of a conserved linkage group syntenic with human chromosome 1q

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1988Publisher:Elsevier BVJournal:Genomics, volume 2, pages 48-56 (issn: 0888-7543, Copyright policy )
Authors: Michael F. Seldin; Alfred D. Steinberg; Renee C. LeBoeuf; Herbert C. Morse;

doi: 10.1016/0888-7543(88)90108-5

pmid: 3384439

Establishment of a molecular genetic map of distal mouse chromosome 1: Further definition of a conserved linkage group syntenic with human chromosome 1q

Abstract

A linkage map of distal mouse chromosome 1 was constructed by restriction fragment length polymorphism analysis of DNAs from seven sets of recombinant inbred (RI) strains. The data obtained with seven probes on Southern hybridization combined with data from previous studies suggest the gene order Cfh, Pep-3/Ren-1,2, Ly-5, Lamb-2, At-3, Apoa-2/Ly-17,Spna-1. These results confirm and extend analyses of a large linkage group which includes genes present on a 20-30 cM span of mouse chromosome 1 and those localized to human chromosome 1q21-32. Moreover, the data indicate similar relative positions of human and mouse complement receptor-related genes REN, CD45, LAMB2, AT3, APOA2, and SPTA. These results suggest that mouse gene analyses may help in detailed mapping of human genes within such a syntenic group.

Related Organizations
Keywords

Genetic Linkage, Chromosome Mapping, Genetic Variation, Proteins, Mice, Inbred Strains, Mice, Genes, Species Specificity, Chromosomes, Human, Pair 1, Animals, Humans, Alleles

  • BIP!
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
78
Average
Top 1%
Top 1%
gold