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Is CD30 a predictive biomarker for brentuximab vedotin?

descriptionPublicationkeyboard_double_arrow_right Article 06 Feb 2017 English Publisher:Informa UK LimitedJournal:Leukemia & Lymphoma, volume 58, pages 1,524-1,525 (issn: 1042-8194, eissn: 1029-2403, Copyright policy )
Authors: Robert, Chen;

doi: 10.1080/10428194.2017.1283687

pmid: 28278730

Is CD30 a predictive biomarker for brentuximab vedotin?

Abstract

Brentuximab vedotin (BV), an antibody–drug conjugate that selectively delivers MMAE into CD30-expressing cells, has shown high response rates in both relapsed/refractory Hodgkin lymphoma (HL) and a...

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Keywords

Brentuximab Vedotin, Immunoconjugates, Humans, Ki-1 Antigen, Antineoplastic Agents, Hodgkin Disease, Biomarkers

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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