
doi: 10.1159/000230564
pmid: 5163553
Primary antihapten response to a monovalent conjugate of NIP (4-hydroxy-3-iodo-5-nitrophenylacetic acid) and bovine serum albumin (BSA) tended to be rich in 7S and primary response to a polyvalent conjugate NIP<sub>34</sub>-BSA rich in 19S anti-NIP antibodies. Monovalent conjugate NIP<sub>1.1</sub>-BSA tended to boost cells primed with polyvalent conjugates of NIP to a secondary anti-NIP response rich in 7S and polyvalent conjugate, NIP<sub>34</sub>-BSA, to a response rich in 19S anti-NIP antibodies. Monovalent conjugate, NIP<sub>1.1</sub>-BSA, did not prime the cells detectably, although it induced a primary antihapten response.
Immunization, Passive, Rats, Inbred Strains, Serum Albumin, Bovine, Nitro Compounds, Antibodies, Rats, Radiation Effects, Immunoglobulin M, Immunoglobulin G, Animals, Female, Immunization, Carrier Proteins, Haptens, Immunologic Memory, Phenylacetates
Immunization, Passive, Rats, Inbred Strains, Serum Albumin, Bovine, Nitro Compounds, Antibodies, Rats, Radiation Effects, Immunoglobulin M, Immunoglobulin G, Animals, Female, Immunization, Carrier Proteins, Haptens, Immunologic Memory, Phenylacetates
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