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Cell Host & Microbe
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Cell Host & Microbe
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License: Elsevier Non-Commercial
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It Takes a Matured mAb to Treat Ebolavirus Infection

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2019 English Publisher:Elsevier BVJournal:Cell Host & Microbe, volume 25, pages 10-12 (issn: 1931-3128, Copyright policy )
Authors: Ami, Patel; David B, Weiner;

doi: 10.1016/j.chom.2018.12.013

pmid: 30629912

It Takes a Matured mAb to Treat Ebolavirus Infection

Abstract

Pan-Ebolavirus immunotherapy would provide a rapid-response treatment during Ebola virus outbreaks. In this issue of Cell Host & Microbe, Wec et al. (2019) and Bornholdt et al. (2019) optimize the MBP134 mAb cocktail through antibody affinity maturation, improving its protective efficacy against three Ebolaviruses: EBOV, SUDV, and BDBV.

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Keywords

Disease Models, Animal, Animals, Antibodies, Monoclonal, Humans, Hemorrhagic Fever, Ebola, Antibodies, Viral, Ebolavirus, Antibodies, Neutralizing

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
hybrid
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