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Toward cloning and mapping the genome of Drosophila

Name: Toward cloning and mapping the genome of Drosophila
Keywords: Gene Rearrangement, Drosophila melanogaster, Genome, Base Sequence, Genes, Mutation, Animals, Chromosome Mapping, Cloning, Molecular, Biological Evolution

descriptionPublicationkeyboard_double_arrow_right Article 11 Oct 1991 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 254, pages 221-225 (issn: 0036-8075, eissn: 1095-9203,

Authors: Michael Ashburner; John R. Merriam; Daniel L. Hartl; FC Kafatos;

doi: 10.1126/science.254.5029.221 , 10.1126/science.1925579

pmid: 1925579

Toward cloning and mapping the genome of Drosophila

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Abstract

An ultimate goal of Drosophila genetics is to identify and define the functions of all the genes in the organism. Traditional approaches based on the isolation of mutant genes have been extraordinary fruitful. Recent advances in the manipulation and analysis of large DNA fragments have made it possible to develop detailed molecular maps of the Drosophila genome as the initial steps in determining the complete DNA sequence.

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Keywords

Gene Rearrangement, Drosophila melanogaster, Genome, Base Sequence, Genes, Mutation, Animals, Chromosome Mapping, Cloning, Molecular, Biological Evolution, Chromosomes

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