The Yeast Checkpoint Kinase Dun1 DownregulatesDIN7in the Absence of DNA Damage
Copyright policy )The Yeast Checkpoint Kinase Dun1 DownregulatesDIN7in the Absence of DNA Damage
Yeast DIN7 is a DNA damage-inducible gene. Its expression is increased in the absence of Dun1, a DNA damage checkpoint kinase. We identified a DIN7 promoter region responsible for Dun1-mediated downregulation and found that DIN7 expression was not further increased in response to hydroxyurea in Deltadun1 cells. Thus DIN7 repression by Dun1 can be released upon DNA damage.
- RIKEN Japan
- Saitama University Japan
Saccharomyces cerevisiae Proteins, Down-Regulation, Cell Cycle Proteins, Saccharomyces cerevisiae, Protein Serine-Threonine Kinases, Exodeoxyribonucleases, Gene Expression Regulation, Fungal, Promoter Regions, Genetic, Protein Kinases, DNA Damage
Saccharomyces cerevisiae Proteins, Down-Regulation, Cell Cycle Proteins, Saccharomyces cerevisiae, Protein Serine-Threonine Kinases, Exodeoxyribonucleases, Gene Expression Regulation, Fungal, Promoter Regions, Genetic, Protein Kinases, DNA Damage
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).2 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!