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Genetic mapping in the mouse of four loci related to thejun family of transcriptional activators

Name: Genetic mapping in the mouse of four loci related to thejun family of transcriptional activators
Keywords: Transcriptional Activation, Transcription, Genetic, Chromosome Mapping, Hybrid Cells, Mice, Inbred C57BL, Mice, Mice, Inbred AKR, Cricetulus, Cricetinae, Multigene Family

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1991 English Publisher:Springer Science and Business Media LLCJournal:Somatic Cell and Molecular Genetics, volume 17, pages 341-347 (issn: 0740-7750, eissn: 1572-9931,

Authors: Christine A. Kozak; Marjorie Shapiro;

doi: 10.1007/bf01233059

pmid: 1887331

Genetic mapping in the mouse of four loci related to thejun family of transcriptional activators

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Abstract

Southern blot analysis of DNAs from somatic cell hybrids and the progeny of an intersubspecies backcross were used to identify and chromosomally map four loci in the mouse containing sequences cross-reactive to members of the jun family of transcriptional activators. The murine homolog of v-jun, Jun, was mapped to chromosome (Chr) 4, and a locus containing jun B-related sequences (Junb) was mapped to Chr 8. Probes for jun D identified two genetic loci; one, Jund-1, is near Junb on Chr 8, and a second, previously unidentified locus termed Jund-2, was mapped to Chr 2.

Related Organizations

National Institute of Health
Pakistan
National Institute of Allergy and Infectious Diseases
United States
National Institutes of Health
United States

Keywords

Transcriptional Activation, Transcription, Genetic, Chromosome Mapping, Hybrid Cells, Mice, Inbred C57BL, Mice, Mice, Inbred AKR, Cricetulus, Cricetinae, Multigene Family, Sequence Homology, Nucleic Acid, Proto-Oncogenes, Animals, Humans, Crosses, Genetic

33 Research products, page 1 of 4

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Protein L-Myc
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Jun protein
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