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Prevalencia de disfunción eyaculatoria secundaria al tratamiento con alfa-bloqueantes en pacientes con hiperplasia benigna de próstata

Authors: Martín-Morales, A.; Meyer, G.; Ramírez, E.;

Prevalencia de disfunción eyaculatoria secundaria al tratamiento con alfa-bloqueantes en pacientes con hiperplasia benigna de próstata

Abstract

Introducción: La hiperplasia benigna de próstata (HBP) se acompaña de síntomas del tracto urinario inferior (STUI) que pueden causar alteraciones eyaculatorias, aunque éstas podrían ser además consecuencia del tratamiento con alfa-bloqueantes. Objetivos: Determinar la prevalencia de disfunción eyaculatoria en pacientes con HBP tratados con alfa-bloqueantes. Secundariamente, evaluar el efecto del tipo de fármaco y la relación de las alteraciones eyaculatorias con factores pronósticos y la gravedad de la HBP. Material y métodos: Estudio epidemiológico, transversal, no controlado y abierto en 1.177 pacientes =40 años diagnosticados de HBP/STUI con más de 6 meses de evolución, tratados con el mismo alfa-bloqueante durante como mínimo los últimos 3 meses. El grado de disfunción eyaculatoria se determinó mediante el dominio sobre eyaculación del Male Sexual Health Questionnaire (MSHQ). Los resultados se estratificaron según la edad y gravedad de la HBP, establecida mediante el International Prostate Symptoms Score (IPSS). Resultados: Se ha estimado una prevalencia de disfunción eyaculatoria del 82,6% en pacientes con HBP/STUI en tratamiento con alfa-bloqueantes. Aunque generalmente leve, un amplio porcentaje de quienes la sufren la consideran un problema. La edad avanzada es el factor más influyente en la gravedad tanto de las alteraciones eyaculatorias como de los síntomas prostáticos. Entre ambos parámetros se ha establecido una sólida correlación. Finalmente, entre los alfa-bloqueantes evaluados, la alfuzosina se ha asociado a una mejor función sexual. Conclusiones: Más del 80% de pacientes con HBP sufren alteraciones eyaculatorias, estrechamente relacionadas con la severidad de los síntomas prostáticos y la edad del individuo. Al establecer tratamiento con alfa-bloqueantes, deberíamos tener en cuenta que la alfuzosina es el que menos impacto tiene sobre la función eyaculatoria.

Related Organizations
Keywords

Urologic Diseases, Sexual Dysfunction, Physiological, Prostatic Hyperplasia, Disfunción eréctil, Hiperplasia benigna de próstata, Enfermedad urológica, Alfuzosina, Síntomas prostáticos, Ejaculation, Tracto urinario inferior, Adrenergic alpha-Antagonists, Alfa-bloqueantes

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    popularity
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    influence
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
Green
hybrid