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Locking in stable states of gene expression: transcriptional control during Drosophila development

Name: Locking in stable states of gene expression: transcriptional control during Drosophila development
Creator: Jeffrey A. Simon
Keywords: Male, Polycomb Repressive Complex 1, 0301 basic medicine, 0303 health sciences, Models, Genetic, Transcription, Genetic, Genes, Homeobox, Gene Expression Regulation, Developmental, Proteins, Genes, Insect

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1995 English Publisher:Elsevier BVJournal:Current Opinion in Cell Biology, volume 7, pages 376-385 (issn: 0955-0674,

Authors: Jeffrey A. Simon;

doi: 10.1016/0955-0674(95)80093-x

pmid: 7662368

Locking in stable states of gene expression: transcriptional control during Drosophila development

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Abstract

Cell fate decisions can be maintained during long periods of developmental time by stable states of gene expression. The Polycomb group and trithorax group proteins of Drosophila are key transcriptional regulators that maintain stable expression states during development. Recent advances in knowledge about individual Polycomb group and trithorax group proteins, their mechanisms of action, and potential homologs in mice and humans are contributing to a greater understanding of their roles in gene expression and development.

Related Organizations

University of Minnesota Morris
United States

Keywords

Male, Polycomb Repressive Complex 1, Models, Genetic, Transcription, Genetic, Genes, Homeobox, Gene Expression Regulation, Developmental, Proteins, Genes, Insect, Mice, Heterochromatin, Animals, Drosophila Proteins, Humans, Drosophila, Female

50 Research products, page 1 of 5

LD16758p
2017IsRelatedTo
Polycomb protein Scm
2017IsRelatedTo
Polyhomeotic-proximal chromatin protein
2017IsRelatedTo
Enhancer of zeste, isoform C
2017IsRelatedTo
GAGA transcription factor factor, 596 isoform
2017IsRelatedTo
GH14582p
2017IsRelatedTo
EG:BACN25G24.3 protein (Fbgn0004860;ph-d protein)
2017IsRelatedTo
Trithorax-like, isoform F
2017IsRelatedTo
Polycomb group protein Pc
2017IsRelatedTo
Additional sex combs, isoform B
2017IsRelatedTo

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	284
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 1%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%