Additional file 2: Fig. S2. Formation of cementum-like and PDL-like tissue in a mouse model. (A) Swine PDLSCs were examined for their multipotent differentiation capacity. Odontogenic (Odon, 5 weeks of stimulus); Ad: adipogenic; and Neuro: neurogenic. Ctrl: control group without differentiation stimulation. (B) Swine or human PDLSCs mixed with HA/TCP and transplanted into SCID mice subQ for 2-3 months and then processed for histology. C: cementum-like. Blue arrows: Sharpey’s fiber-like or collagen bundles in PDL-like tissues. Scale bar: (A) Top/middle panels: 200 µm; bottom panel: 50 µm; (B) top panel: 500 µm, middle: 100 µm; bottom: 50 µm. Differentiation and staining protocols followed studies published previously [47, 48].