Long-range interaction between the P2.1 and P9.1 peripheral domains of the Tetrahymena ribozyme
Copyright policy )Long-range interaction between the P2.1 and P9.1 peripheral domains of the Tetrahymena ribozyme
The Tetrahymena ribozyme possesses peripheral domains, termed P9.1 and P9.2. They are nonessential in the mechanism of the catalytic reaction but contribute to enhance the catalytic activity of the ribozyme. It has been postulated that P9.1 is capable of forming Watson-Crick base pairings with another peripheral domain, P2.1. We report here the existence of long-range base pairings between the loop regions of these two domains and show that this interaction apparently plays a role in enhancing the catalytic activity of the ribozyme.
- Kyoto University Japan
Base Composition, Base Sequence, RNA, Ribosomal, RNA Splicing, Molecular Sequence Data, Tetrahymena, Animals, Nucleic Acid Conformation, RNA, Catalytic, Catalysis
Base Composition, Base Sequence, RNA, Ribosomal, RNA Splicing, Molecular Sequence Data, Tetrahymena, Animals, Nucleic Acid Conformation, RNA, Catalytic, Catalysis
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).12 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!