The complete DNA sequence of yeast chromosome III
Copyright policy )The complete DNA sequence of yeast chromosome III
The entire DNA sequence of chromosome III of the yeast Saccharomyces cerevisiae has been determined. This is the first complete sequence analysis of an entire chromosome from any organism. The 315-kilobase sequence reveals 182 open reading frames for proteins longer than 100 amino acids, of which 37 correspond to known genes and 29 more show some similarity to sequences in databases. Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
- Ludwig-Maximilians-Universität München Germany
- Ghent University Belgium
- Roma Tre University Italy
- Trinity College Dublin Ireland
- University of Rome Tor Vergata Italy
Base Sequence, Genes, Fungal, Molecular Sequence Data, Chromosome Mapping, RNA, Fungal, Saccharomyces cerevisiae, Open Reading Frames, RNA, Transfer, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology; name=Manchester Institute of Biotechnology, Manchester Institute of Biotechnology, Chromosomes, Fungal, Base Sequence; RNA, Transfer; Genes, Fungal; Open Reading Frames; RNA, Fungal; Molecular Sequence Data; Chromosome Mapping; Saccharomyces cerevisiae; Chromosomes, Fungal
Base Sequence, Genes, Fungal, Molecular Sequence Data, Chromosome Mapping, RNA, Fungal, Saccharomyces cerevisiae, Open Reading Frames, RNA, Transfer, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology; name=Manchester Institute of Biotechnology, Manchester Institute of Biotechnology, Chromosomes, Fungal, Base Sequence; RNA, Transfer; Genes, Fungal; Open Reading Frames; RNA, Fungal; Molecular Sequence Data; Chromosome Mapping; Saccharomyces cerevisiae; Chromosomes, Fungal
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