
handle: 10281/278 , 10281/34701
A connection is made between certain multiple-sequence alignment problems and facility-location problems, and the existence of a PTAS (polynomial-time approximation scheme) for these problems is shown. Moreover, it is shown that multiple sequence alignment with SP-score and fixed gap penalties is MAX SNP-hard.
analysis of algorithms; computational complexity; facilities-equipment planning; location, multiple sequence location
analysis of algorithms; computational complexity; facilities-equipment planning; location, multiple sequence location
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