<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

RGG motif proteins: Modulators of mRNA functional states

descriptionPublicationkeyboard_double_arrow_right Article 15 Jan 2012Publisher:Informa UK LimitedJournal:Cell Cycle, volume 11, pages 2,594-2,599 (issn: 1538-4101, eissn: 1551-4005,

Authors: Roy Parker; Purusharth I. Rajyaguru;

doi: 10.4161/cc.20716

pmid: 22767211

pmc: PMC3873214

RGG motif proteins: Modulators of mRNA functional states

- Summary
- Subjects
- Related research
  (7)
- Metrics

Abstract

A recent report demonstrates that a subset of RGG-motif proteins can bind translation initiation factor eIF4G and repress mRNA translation. This adds to the growing number of roles RGG-motif proteins play in modulating transcription, splicing, mRNA export and now translation. Herein, we review the nature and breadth of functions of RGG-motif proteins. In addition, the interaction of some RGG-motif proteins and other translation repressors with eIF4G highlights the role of eIF4G as a general modulator of mRNA function and not solely as a translation initiation factor.

Related Organizations

University of Arizona
United States
Howard Hughes Medical Institute
United States

Keywords

Protein-Arginine N-Methyltransferases, Saccharomyces cerevisiae Proteins, Amino Acid Motifs, Nuclear Proteins, RNA-Binding Proteins, Saccharomyces cerevisiae, Eukaryotic Initiation Factor-4E, Ribonucleoproteins, Protein Biosynthesis, RNA, Messenger, Eukaryotic Initiation Factor-4G

7 Research products, page 1 of 1

Single-stranded nucleic acid-binding protein
2017IsRelatedTo
ATP-dependent RNA helicase DED1
2017IsRelatedTo
Nuclear polyadenylated RNA-binding protein 4
2017IsRelatedTo
Protein SCD6
2017IsRelatedTo
Nucleolar protein 3
2017IsRelatedTo
Eukaryotic initiation factor 4F subunit p130
2017IsRelatedTo
Eukaryotic initiation factor 4F subunit p150
2017IsRelatedTo

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	84
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%